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Table 1 Intensity and extent of p53 immunopositivity in CNS embryonal tumors

From: Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus

Case

Tumor Subtype

p53 Intensity

p53 Positive Cells

1

Classic MB

1

5 to 25%

2

Classic MB

1

5 to 25%

3

Classic MB

1

5 to 25%

4

Classic MB

1

5 to 25%

5

Classic MB

1

5 to 25%

6

Nodular MB

1

5 to 25%

7

Nodular MB

1

5 to 25%

8

Nodular MB

1

5 to 25%

9

Moderately Anaplastic MB

1

5 to 25%

10

Moderately Anaplastic MB

1

5 to 25%

11

Moderately Anaplastic MB

1

5 to 25%

12

Moderately Anaplastic MB

1

5 to 25%

13

Moderately Anaplastic MB

1

5 to 25%

14

Moderately Anaplastic MB

1

5 to 25%

15

Severely Anaplastic MB

2

51 to 75%

16

Severely Anaplastic MB

2

51 to 75%

17

Severely Anaplastic MB

2

26 to 50%

18

sPNET

1

5 to 25%

19

sPNET

1

5 to 25%

20

sPNET

1

5 to 25%

21

sPNET

2

5 to 25%

22

sPNET/Medulloepithelioma

1

5 to 25%

23A

sPNET/Medulloepithelioma

2

51 to 75%

23B

sPNET/Medulloepithelioma

2

76 to 100%

24

AT/RT

1

5 to 25%

25

AT/RT

2

26 to 50%

  1. MB – medulloblastoma; sPNET – supratentorial PNET; AT/RT – atypical teratoid/rhabdoid tumor; p53 Intensity (0 – negative, 1 – weak, 2 – strong).