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Table 1 Intensity and extent of p53 immunopositivity in CNS embryonal tumors

From: Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus

Case Tumor Subtype p53 Intensity p53 Positive Cells
1 Classic MB 1 5 to 25%
2 Classic MB 1 5 to 25%
3 Classic MB 1 5 to 25%
4 Classic MB 1 5 to 25%
5 Classic MB 1 5 to 25%
6 Nodular MB 1 5 to 25%
7 Nodular MB 1 5 to 25%
8 Nodular MB 1 5 to 25%
9 Moderately Anaplastic MB 1 5 to 25%
10 Moderately Anaplastic MB 1 5 to 25%
11 Moderately Anaplastic MB 1 5 to 25%
12 Moderately Anaplastic MB 1 5 to 25%
13 Moderately Anaplastic MB 1 5 to 25%
14 Moderately Anaplastic MB 1 5 to 25%
15 Severely Anaplastic MB 2 51 to 75%
16 Severely Anaplastic MB 2 51 to 75%
17 Severely Anaplastic MB 2 26 to 50%
18 sPNET 1 5 to 25%
19 sPNET 1 5 to 25%
20 sPNET 1 5 to 25%
21 sPNET 2 5 to 25%
22 sPNET/Medulloepithelioma 1 5 to 25%
23A sPNET/Medulloepithelioma 2 51 to 75%
23B sPNET/Medulloepithelioma 2 76 to 100%
24 AT/RT 1 5 to 25%
25 AT/RT 2 26 to 50%
  1. MB – medulloblastoma; sPNET – supratentorial PNET; AT/RT – atypical teratoid/rhabdoid tumor; p53 Intensity (0 – negative, 1 – weak, 2 – strong).