Figure 1From: Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus p53 Immunostaining in CNS embryonal tumors. Most p53 immunopositivity was relatively faint and present only in a small fraction of the tumor. This nodular medulloblastoma had weak staining in less than 25% of cells (A). Some anaplastic medulloblastomas had strong p53 immunostaining in a larger fraction of cells (B). Most AT/RT and supratentorial PNET contained p53 immunopositive cells, like this lesion metastatic within the CNS in which almost all cells are strongly positive (C). Note the lack pf staining in non-neoplastic stroma (Asterisk).Back to article page