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Figure 1 | BMC Cancer

Figure 1

From: Membrane testosterone binding sites in prostate carcinoma as a potential new marker and therapeutic target: Study in paraffin tissue sections

Figure 1

Prostate carcinoma staining with testosterone-BSA-FITC. Representative patterns of prostate carcinoma tissue section staining with testosterone-BSA-FITC in absence of BSA and cyproterone acetate preincubation (upper panel) or in presence of cyproterone acetate and in absence of BSA (lower panel). As explained in the text, BSA preincubation decreases or eliminates non-specific interactions of the tracer (testosterone-BSA-FITC) with prostate stroma or cell membranes, while the antiandrogen cyproterone acetate binds selectively to iAR.

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