Study | Country | N (# cases) | Age (yrs) | Paternal age (PA) | RR | Maternal age (MA) | RR | Adjusting | Restricted | |
---|---|---|---|---|---|---|---|---|---|---|
Mutually* | Covariates† | |||||||||
Cohort study | ||||||||||
Colditz et al, 1991 | US | 118,309 (1,976) | 3055 | ≥39 vs. <20 | 0.9 (0.56–1.45) | ≥39 vs. <20 | 0.9 (0.57–1.39) | YES | YES | - |
Zhang et al, 1995 | US | 2,662 (149) | 29–62 | ≥36 vs. <29 | 0.8 (0.5–1.4) | 26–31 vs. <26 | 1.5 (1.0–2.4) | - | YES | - |
Holmberg et al1, 1995 | US | 384,769 (1,967) | - | ≥45 vs. <20 | 0.8 (0.48–1.28) | ≥45 vs. <20 | 1.3 (0.85–1.98) | - | YES | - |
Hemminki et al, 1999 | Sweden | 3,800,000 (8,877) | 15–53 | 40–49 vs. <25 | 1.1 (0.94–1.18) | 40–49 vs. <20 | 1.1 (0.91–1.27) | YES | - | PA in sporadic cases |
Hilakivi-Clarke et al, 2001 | Finland | 3,447 (177) | - | - | - | - | NS | - | - | - |
Study | Country | Cases/controls | Age (yrs) | Paternal age (PA) | OR | Maternal age (MA) | OR | Adjusting | Remark | |
Mutually* | Covariates† | |||||||||
Case-control study | ||||||||||
Standfast et al, 1967 | US | 229/229 | 40–44 | - | - | 29.1 vs. 28.2 | 2p < 0.05 | - | - | - |
Henderson et al, 1974 | US | 308/308 | <64 | 31.5 vs. 30.7 | NS | 27.3 vs. 26.3 | P < 0.01 | - | - | - |
Rothman et al, 1980 | International | 4339/12760 | - | - | - | 35–39 vs. <20 | 1.30 | - | YES | - |
Baron et al, 1984 | UK | 971/971 | ≤50 | - | - | 21–25 vs. ≤20 | 1.4 (0.92–2.18) | - | YES | - |
Le Marchand et al, 1988 | US | 153/461 | <45 | 36–59 vs. 19–26 | 1.4 (0.81–2.41) | 30–46 vs. 23–26 | 1.7 (0.99–2.78) | - | - | Pts <33 yrs |
Janerich et al, 1989 | US | 801/2647 | - | Per 10-yrs | 1.2 (1.07–1.33) | Each 10-yrs | 1.2 (1.09–1.41) | - | - | - |
Thompson et al, 1990 | US | 2492/2687 | 20–54 | - | - | 35–39 vs. <20 | 1.5 (1.10–1.93) | - | YES | parous |
Hsieh et al, 1991 | International | 927/2616 | ≥35 | - | - | Each 5-yrs | 1.1 (1.01–1.10) | - | YES | postmenopause |
Ekbom et al, 1992 | Sweden | 458/1197 | ≥35 | - | - | Each 5-yrs | 1.0 (0.92–1.12) | - | - | - |
Janerich et al, 1994 | US | 2414/9138 | - | ≥45 vs. <25 | 1.0 (0.76–1.28) | ≥40 vs. <20 | 1.1 (0.87–1.37) | - | YES | - |
Sanderson et al, 1995 | US | 1147/1399 | 21–45, 50–64 | - | - | ≥35 vs. <25 | 1.0 (0.7–1.4), 1.0 (0.7–1.5) | - | - | - |
Ekbom et al, 1997 | Sweden | 1068/2727 | - | - | - | Each 5-yrs | 1.1 (0.99–1.14) | - | - | - |
Newcomb et al, 1997 | US | 1253/1121 | - | ≥40 vs. ≤24 | 0.9 (0.68–1.24) | ≥40 vs. ≤20 | 0.9 (0.62–1.37) | - | YES | - |
Weiss et al, 1997 | US | 2173/1990 | 20–55 | - | - | ≥35 vs. <20 | 0.9 (0.7–1.3) | - | YES | - |
Innes et al, 2000 | US | 484/2870 | 14–37 | ≥40 vs. 25–29 | 1.5 (1.03–2.23) | ≥35 vs. 20–24 | 1.9 (1.18–3.18) | YES | - | - |
Titus-Ernstoff et al, 2002 | US | 5629/5928 | 50–79 | - | - | ≥40 vs. 25–29 | 1.3 (0.90–1.79) | - | - | postmenopause |
Mellemkjǽr et al, 2003 | Denmark | 881/3423 | <40 | - | - | ≥30 vs. <25 | 1.1 (0.90–1.36) | - | - | - |
Hodgson et al, 2004 | US | 280/236 | 18–74 | 35–56 vs. 23–27 | 1.5 (0.7–3.2) | ≥23–27 vs. 19–22 | 3.5 (2.0–5.9) | YES | - | PA in African American |