Case | a BRCA1 carrier type | Stage | bGrade | Type | TTGE | Exon | Codon | Mutation | aa change | Age of diagnosis | cSurvival months | dVital status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
3453 | 1 | 3 | 2 | ser | pos | 5 | Â | 559+1G>A | splice | 53 | 83 | 1 |
10 | 1 | 3 | 3 | ser | pos | 6 | 213 | CGA>TGA | arg>stop | 65 | 22 | 3 |
2857 | 1 | 3 | 3 | ser | pos | 6 | 213 | CGA>TGA | arg>stop | 53 | 83 | 3 |
4 | 1 | 4 | 3 | ser | pos | 6 | 216 | GTG>ATG | val>met | 59 | 11 | 3 |
27 | 1 | 2 | 3 | endo | pos | 7 | 237 | ATG>ATA | met>ile | 39 | 61 | 3 |
8 e | 1 | 3 | 3 | ser | pos | 7 | 260 | TCC>TCT | ser>ser | 49 | 84 | 3 |
 |  |  |  |  |  | 8 | 306 | CGA>TGA | arg>stop |  |  |  |
14 | 1 | 1 | 3 | ser | pos | 8 | 267 | CGG>CAG | arg>gln | 51 | 25 | 3 |
13 | 1 | 4 | 3 | ser | pos | 8 | 273 | CGT>AGT | arg>ser | 39 | 15 | 3 |
29 | 1 | 3 | 3 | mix | pos | 8 | 273 | CGT>TGT | arg>cys | 50 | 36 | 3 |
2842 | 1 1 | 4 | 3 | ser | pos | 8 | 273 | CGT>TGT | arg>cys | 39 | 35 | 3 |
21 | 1 | 3 | 3 | ser | pos | 8 | 293 | GGG>AGG | gly>arg | 39 | 21 | 3 |
26 | 1 | 3 | 2 | ser | pos | Â | intron | G>A | ivs5 | 53 | 93 | 1 |
9 | 1 | 4 | 2 | ser | neg | Â | Â | Â | Â | 50 | 39 | 3 |
11 | 1 | 3 | 3 | ser | neg | Â | Â | Â | Â | 44 | 8 | 3 |
17 | 1 | 3 | 3 | ser | neg | Â | Â | Â | Â | 47 | 30 | 3 |
24 | 1 | 2 | 4 | ser | neg | Â | Â | Â | Â | 59 | 20 | 3 |
34 | 1 | 1 | 3 | ser | neg | Â | Â | Â | Â | 46 | 120 | 1 |
30 | 1 | 1 | 2 | ser | neg | Â | Â | Â | Â | 43 | 199 | 2 |
32 | 1 | 2 | 3 | ser | neg | Â | Â | Â | Â | 48 | 108 | 1 |
3351 | 1 | 4 | 3 | endo | neg | Â | Â | Â | Â | 44 | 9 | 3 |
1 | 2 | 4 | 3 | ser | pos | 5 | 144 | CAG>TAG | gln>stop | 41 | 1 | 3 |
3 | 2 | 3 | 3 | uncl | pos | 6 | 196 | CGA>TGA | arg>stop | 48 | 46 | 3 |
20 | 2 | 3 | 3 | ser | pos | 6 | 205 | TAT>TCT | tyr>ser | 52 | 36 | 3 |
28 | 2 | 4 | 3 | ser | pos | 7 | 261 | AGG>AGA | arg>arg | 80 | 12 | 3 |
7 e | 2 | 3 | 3 | ser | pos | 7 | 255 | ATC>GTC | ile>val | 58 | 30 | 3 |
 |  |  |  |  |  | 5 | 141 | TGC>TGT | cys>cys |  |  |  |
12 | 2 | 1 | 3 | ser | pos | 8 | 280 | AGA>GGA | arg>gly | 49 | 134 | 1 |
15 | 2 | 3 | 3 | ser | pos | Â | intron | C>T | ivs7 | 50 | 19 | 3 |
5 | 2 | 4 | 3 | ser | neg | Â | Â | Â | Â | 60 | 45 | 3 |
18 | 2 | 2 | 3 | endo | neg | Â | Â | Â | Â | 44 | 117 | 3 |
22 | 2 | 3 | 2 | mix | neg | Â | Â | Â | Â | 47 | 96 | 3 |