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Table 4 Results of GAM and proportional hazards tests for GBSG-2 data

From: Modeling the effect of age in T1-2 breast cancer using the SEER database

GBSG-2 data set no transform transform age+|age-50|1.5 transform age+|age-50|1.8
Hazard ratio for Age 1.001 1.004 1.002
p-value of Hazard ratio for Age 0.92 0.019 0.010
GAM Chisq for Age 31.74 9.29 8.70
GAM p-value for Age 0.0000006 0.0256 0.0336
Test PH for Age: rho 0.131 0.0459 0.0240
Test PH for Age: chisq 6.118 0.581 0.169
Full PH model Rsquare 0.135 0.142 0.143
Full PH model Likelihood ratio test 99.7 105 106
  1. Chisq = chi-square value, GAM = generalized additive model, GBSG-2 = German Breast Cancer Study Group, PH = proportional hazards. The Additional file 2 "outputgbsg2.doc" lists the other covariates included in the PH models.