Table 3 Combined effect of XRCC1, XRCC3 and XPD genes upon colorectal cancer risk

With Gln

With Met

Lys/Lys

18

34

1.00

1.00

Arg/Arg

With Met

Lys/Lys

30

30

1.91 (0.89–4.10)

With Gln

Thr/Thr

Lys/Lys

239

257

1.77 (0.97–3.22)

1.79 (0.99–3.24)

With Gln

With Met

With Gln

6

6

1.90 (0.54–6.76)

Arg/Arg

Thr/Thr

Lys/Lys

312

307

1.93 (1.07–3.50)

Arg/Arg

With Met

With Gln

7

5

2.65 (0.74–9.56)

1.95 (1.08–3.52)

With Gln

Thr/Thr

With Gln

48

46

1.99 (0.99–4.01)

Arg/Arg

Thr/Thr

With Gln

54

42

2.43 (1.21–4.90)

2.43 (1.21–4.90) 0.03^b