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Table 3 Combined effect of XRCC1, XRCC3 and XPD genes upon colorectal cancer risk

From: Polymorphisms of the XRCC1, XRCC3, & XPDgenes, and colorectal cancer risk: a case-control study in Taiwan

XRCC1 Arg399Gln XRCC3 Thr241Met XPD Lys751Gln Cases Controls OR (95% CI)a OR (95% CI)a
With Gln With Met Lys/Lys 18 34 1.00 1.00
Arg/Arg With Met Lys/Lys 30 30 1.91 (0.89–4.10)  
With Gln Thr/Thr Lys/Lys 239 257 1.77 (0.97–3.22) 1.79 (0.99–3.24)
With Gln With Met With Gln 6 6 1.90 (0.54–6.76)  
Arg/Arg Thr/Thr Lys/Lys 312 307 1.93 (1.07–3.50)  
Arg/Arg With Met With Gln 7 5 2.65 (0.74–9.56) 1.95 (1.08–3.52)
With Gln Thr/Thr With Gln 48 46 1.99 (0.99–4.01)  
Arg/Arg Thr/Thr With Gln 54 42 2.43 (1.21–4.90) 2.43 (1.21–4.90) 0.03b
  1. a: ORs and 95% CIs were estimated from unconditional logistic regressions, controlling for age and gender
  2. b: Trend test