Schematic representation of the domain architecture and common features in representative proteins containing the ACRATA domain. The representative sequences selected correspond to: YEDZ, SW:YEDZ_ECOLI; STEAP, SW:STEA_HUMAN; TSAP6, SP:Q80ZF3; NOX1, SW:NOX1_HUMAN; NOX5, SP:Q96PH2; DUOX1, SP:Q9NRD9. NOX1, NOX5, and DUOX1, belong to the Nox family. The proteins are drawn approximately to scale. The domains are named and located according to the Pfam and SMART protein domain databases [34-37]. Abbreviations: SP, SPTREMBL; SW, SWISSPROT.