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Table 1 p16INK4a EXPRESSION IN NORMAL, DYSPLASTIC AND NEOPLASTIC EPITHELIAL CELLS OF CERVIX UTERI

From: Protein p16 as a marker of dysplastic and neoplastic alterations in cervical epithelial cells

   STAINING*
MATERIALS number of samples negative poor sporadic focal diffuse
Normal epithelium (smears) 6 6 (100) - - - -
Cervical ectopia including 37 34 (91,9) 3 (8,1) - - -
C.e. + coilocytosis 10 9 1 - - -
C.e. + condyloma 2 1 1 - - -
Dysplasia:       
CINs I 51 32 (62,7) 12 (23,5) 6 (11,8) 1 (2,0) -
CINs II 38 26 (68,4) 7 (18,4) 4 (10,5) 1 (2,7) -
CINs III including cancer in situ 24 8 (33,3) 3 (12,5) 7 (29,2) 2 (8,3) 4 (16,7)
Invasive carcinomas including squamous cell carcinomas adenocarcinomas 26 1 (3,8) 1 (3,8) 4 (15,5) 7 (26,9) 13 (50,0)
Squamous cell carcinomas 21 1 (4,8) 1 (4,8) 3 (14,3) 6 (28,5) 10 (47,6)
Adenocarcinomas 5 - - 1 (20,0) 1 (20,0) 3 (60,0)
  1. * percent is given in parenthesis