Treatment | Target:Control Ratio | |||||
---|---|---|---|---|---|---|
24 Hour | 48 Hour | |||||
MT1-MMP ± SEM | MMP-11 ± SEM | 18S rRNA ± SEM | MT1-MMP ± SEM | MMP-11 ± SEM | 18S rRNA ± SEM | |
Control | 1.00 ± 0.02 | 1.00 ± 0.02 | 1.00 ± 0.02 | 1.00 ± 0.08 | 1.00 ± 0.04 | 1.00 ± 0.05 |
Collagen I | 1.00 ± 0.08 | 1.38 ± 0.18 | 0.90 ± 0.04 | 0.84 ± 0.06 | 1.20 ± 0.10 | 0.94 ± 0.04 |
Collagen IV | 1.10 ± 0.06 | 1.65 ± 0.08 | 0.58 ± 0.06 | 1.00 ± 0.08 | 1.45 ± 0.12 | 0.60 ± 0.05 |
Collagen V | 1.04 ± 0.10 | 1.65 ± 0.08 | 0.60 ± 0.06 | 0.90 ± .004 | 1.80 ± 0.10 | 0.56 ± 0.02 |
Con-A | 1.20 ± 0.14 | 0.66 ± 0.12 | 0.78 ± 0.08 | 0.95 ± 0.08 | 0.85 ± 0.10 | 0.80 ± 0.04 |
TGF-β | 0.90 ± 0.06 | 0.56 ± 0.06 | 0.60 ± 0.02 | 0.84 ± 0.08 | 0.75 ± 0.05 | 0.64 ± 0.08 |
Fibronectin | 1.07 ± 0.12 | 0.71 ± 0.08 | 0.58 ± 0.02 | 0.95 ± 0.32 | 0.95 ± 0.07 | 0.64 ± 0.04 |
IL-1β | 1.34 ± 0.02 | 0.65 ± 0.04 | 0.55 ± 0.02 | 1.45 ± 0.16 | 1.86 ± 0.20 | 0.55 ± 0.03 |
IL-2 | 0.88 ± 0.20 | 0.66 ± 0.08 | 0.50 ± 0.02 | 0.96 ± 0.04 | 1.50 ± 0.10 | 0.56 ± 0.06 |
IL-6 | 1.03 ± 0.04 | 0.72 ± 0.04 | 0.65 ± 0.02 | 0.75 ± 0.06 | 1.15 ± 0.12 | 0.60 ± 0.02 |