Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma

Table 1 Patient and biopsy information from the tumors of paired (tumor and normal from the same breast) tissue samples.

Patient No.	Diagnosis^a	SBR Grade^b	Age	ER^c	PR^c	Malignant lymph nodes^d
1	IDC	III/III	43	-	-	NS
2	IDC	III/III	55	-	-	0/11
3	IDC	III/III	67	-	-	0/17
4	IDC	III/III	49	-	-	NS
5	IDC	III/III	59	+++	+++	0/9
6	IDC	III/III	75	-	-	0/10
7	IDC	II/III	60	-	-	15/15
8	IDC	III/III	34	-	-	1/15
9	IDC	III/III	70	++++	-	0/5
10	IDC	II/III	69	na	na	0/16
11	IDC	III/III	49	++	+	0/8

^a IDC: infiltrating duct carcinoma ^b SBR: Scarff-Bloom-Richardson histological grading system ^c ER and PR concentration codes: - receptor values less than 24 + receptor values between 25 and 99 ++ receptor values between 100 and 249 +++ receptor values between 250 and 549 ++++ receptor values > 550 ^d Number of lymph nodes assessed as malignant out of total number examined na: not available NS: No lymph nodes submitted with specimen

ISSN: 1471-2407