Association of HLA Class I and Class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11)

Table 4 e1a2 association with HLA Class I and II in leukemia patients and healthy donors with statistical analysis

HLA	ALLELE	LEUKEMIA PATIENTS*	HEALTHY DONORS*	RELATIVE RISK	CHI-SQUARE	BINDING SCORE
A	01	9	78	3.18	8.91	5
A	02	6	275	0.38	4.76	8
A	11	4	27	3.65	5.93	3
A	26	3	16	4.54	6.37
A	68	0	107	0.00	5.48	3
B	08	6	45	3.36	7.27	7
B	14	0	99	0.00	5.13	7
B	49	1	2	11.35	6.11
B	53	1	3	7.56	4.15	3
B	62	3	0	22530000.00	66.52	2
DQB1	0201	7	36	3.61	8.85
DQB1	0502	2	4	8.33	8.12
DRB1	0301	7	36	3.61	8.85
DRB1	0401	0	56	0.00	3.93
DRB1	0802	1	1	16.24	6.95
DRB1	1601	2	2	16.72	13.96

*Figures shown are the gene frequencies. For a significance level of = 0.05 needed to reject the null hypothesis, the chi square statistic must be > 3.84.

ISSN: 1471-2407