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Table 2 Clinical response rate of patients stratified by TS mRNA level.

From: Thymidylate synthetase mRNA levels are increased in liver metastases of colorectal cancer patients resistant to fluoropyrimidine-based chemotherapy

TS mRNA level

Clinical response rate*


4/10, 40%


2/10, 20%

p value

p = 0.01

  1. *Clinical response is defined as CR or PR.