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Table 1 Clinical characteristics of CRC patients with nonresectable liver metastases.

From: Thymidylate synthetase mRNA levels are increased in liver metastases of colorectal cancer patients resistant to fluoropyrimidine-based chemotherapy

Patient Age (years)/sex Response Survival duration (months) TS expression* before treatment TS expression* after treatment
1 50/F PD 4 4 11
2 70/M PD 20 4 12
3 69/F PD 17 5 21
4 61/M PD 20 12 34
5 44/F PD 27 15 47
6 53/M PD 5 10 9
7 56/F PD 9 23 ND
8 58/M PD 7 14 ND
9 60/F PD 13 15 ND
10 52/M SD 11 9 14
11 79/M SD 25 17 ND
12 49/F SD 34 32 ND
13 63/M SD 8 20 ND
14 56/F SD 5 19 ND
15 51/F PR 17 20 ND
16 65/M PR 21 6 ND
17 55/M PR 17 8 ND
18 70/M PR 28 15 ND
19 73/F PR 81 8 ND
20 65/M CR 47 8 ND
  1. * This value is expressed in arbitrary units; F, female; M, male; PD, progression disease; SD, stable disease; PR, partial response; CR, complete response; ND, not determined.