Table 7 Endothelial markers expressed in normal and tumour endothelial cells (ECs) and in KS. For comparison tag numbers for each group were normalized to 100,000 transcripts. Endothelial markers were derived from [22]. Tumour endothelial markers derived from colon cancer endothelium are shown in bold.

CATATCATTAA

Angiomodulin

247

501

120

TGCACTTCAAG

Hevin

328

141

90

TTTGCACCTTT

Connective tissue growth factor

165

84

41

TTGCTGACTTT

Collagen, type VI α1

73

131

101

ACCATTGGATT

Interferon induced transmembrane protein

102

67

19

ACACTTCTTTC

Guanine nucleotide binding protein 11

104

44

35

TTCTGCTCTTG

Von Willebrand factor

71

67

49

TCCCTGGCAGA

Cysteine-rich protein 2 (CRP-2, ESP-1)

66

68

8

TAATCCTCAAG

Collagen, type XVIII α

26

106

26

ATGTCTTTTCT

Insulin-like growth factor-binding protein 4

58

65

19

GGGATTAAAGC

CD146 endothelial marker

40

67

0

TTAGTGTCGTA

SPARC (osteonectin, BM-40

38

69

22

TTCTCCCAAAT

Collagen, type IV α2

20

86

9

GTGCTAAGCGG

Collagen, type VI α2

24

74

9

GTTTATGGATA

Matrix Gla protein (MGP)

35

56

22

CCCTGTTCAGC

TIE-1

14

15

13

CCCTTGTCCGA

PEM1 EST

131

104

11

CCCTTTCACAC

PEM2 EST

52

33

3

CAACAATAATA

PEM3 EST

42

25

4

GGCCCTACAGT

PEM4 EST

26

13

5

GCTAACCCCTG

PEM5 EST

7

31

9

GGCACTCCTGT

PEM6 EST

22

13

4

TCACAGCCCCC

PEM7 EST

20

15

8

TTTCATCCACT

PEM8 EST

20

13

3

ATACTATAATT

PEM9 EST

25

6

0

AATAGGGGAAA

PEM10 EST

13

19

3

GGAAATGTCAA

MMP-2 (gelatinase A, 72-kD type IV collagenase)

1

31

52

TTTGGTTTTCC

Collagen, type I α2, transcript A

5

139

110

ATTTTGTATGA

Nidogen (entactin)

0

13

6

ACTTTAGATGG

Collagen, type VI α3

1

23

66

GAGTGAGACCC

Thy-1 cell surface antigen

3

63

33

TTAAATAGCAC

Collagen, type I α1

2

33

2

GTTCCACAGAA

Collagen, type I α2, transcript B

0

9

19

TCCCCCAGGAG

Bone morphogenetic protein 1 (metalloprotease)

1

164

0

CTTTCTTTGAG

Regulated in glioma-like 7–1

0

22

1

CAGGAGACCCC

MMP-11 (stromelysin 3)

0

16

1

GTACACACACC

Cystatin S

0

10

0

CCACAGGGGAT

Collagen, type III α1

2

38

182

GGGGCTGCCCA

TEM1, similarity to thrombomodulin

0

28

26

GATCTCCGTGT

TEM2, similarity to rat Rhes ras-related protein

0

25

0

CATTTTTATCT

TEM3, ESTs

0

23

1

TATTAACTCTC

TEM4, similarity to JNK interacting protein-3a

0

21

2

TTTTTAAGAAC

TEM5, ESTs

0

14

0

TTAAAAGTCAC

TEM6, ESTs

1

19

1

ACAGACTGTTA

TEM7, similarity with sea squirt nidogen

4

74

2

CTATAGGAGAC

TEM8, similarity with homeobox protein DLX-3

1

18

8

GCCCTTTCTCT

TEM9, Endo 180 lectin (macrophage mannose receptor family)

1

17

13