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Table 8 Bladder

From: Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis

Author Cases N Controlsa/Cohortb Source Population Exposure definition Exposure assessment Drug RR 95% CI
Castelao et al. [25] 1,514 1,514a Population based >2 days/week for >1 month Personal Interview Aspirin (12%) 0.85 0.66–1.09
       NSAIDs (39%) 0.81 0.68–0.96
Langman et al. [36] 1,041 3,122a Population based >7 prescriptions during months 13–36 before index date Automated Database NSAIDs (7%) 1.14 0.85–1.53
Rosenberg[56] 1,110 4,906a Hospital based >3 days/week for >3 months 1.5 years of lag time Personal Interview NSAIDs (6%) 0.8 0.4–1.6
Paganini-Hill et al. [40] 93 13,987b Cohort Daily use of aspirin for an undefined time Mailed questionnaire Aspirin (16%) 1.10§ 0.65–1.85
Schreinemachers et al. [43] 35 12,668b Cohort Ever use of aspirin in the 30 days prior to start date Personal Interview Aspirin (59%) 1.06 0.54–2.09
  1. Prevalence of exposure among controls/cohort; Exclusive users of aspirin.