Table 6 Prostate
Author | Cases n | Controlsa/Cohortb | Source population | Exposure definition | Exposure assessment | Drug | RR | 95% CI |
|---|---|---|---|---|---|---|---|---|
Nelson et al. [38] | 417 | 420a | Hospital based | >1 tablet/day in the year prior to admission | Personal Interview | NSAIDs (15%) | 0.34 | 0.20–0.58 |
Langman et al. [36] | 1,813 | 5,354a | Population based | >7 prescriptions during months 13–36 before index date | Automated Database | NSAIDs (7%) | 1.33 | 1.07–1.64 |
Norish et al. [39] | 317 | 480a | Population based | >1 tablet/week | Mailed Questionnaire | Aspirin (29%) | 0.85 | 0.61–1.19 |
|  |  |  |  |  |  | NA-NSAIDs (7%) | 0.87 | 0.49–1.55 |
|  |  |  |  |  |  | NSAIDs (36%) | 0.88 | 0.64–1.20 |
Irani et al. [53] | 639 | 659a | Hospital based | Ever use | In-hospital Questionnaire | NA-NSAIDs (46%) | 0.80 | 0.66–1.07 |
Neugut et al. [62] | 319 | 189a | Hospital based | Chronic aspirin use | Medical records | Aspirin (7%) | 1.60 | 0.82–3.11 |
Roberts et al. [41] | 91 | 1,362b | Cohort | Daily use | Mailed Questionnaire | NSAIDs (42%) | 0.37 | 0.22–0.62 |
Paganini-Hill et al. [40] | 149 | 5,106b | Cohort | Daily use of aspirin for an undefined time | Mailed Questionnaire | Aspirin (17%) | 0.94§ | 0.61–1.44 |
Thun et al. [46]†| N.R. | 290,681b | Cohort | More than 16 times per month for at least one year | Mailed Questionnaire | Aspirin (11%) | 0.82 | 0.56–1.19 |
Schreinemachers et al. [43] | 123 | 5,179b | Cohort | Ever use of aspirin in the 30 days prior to start date | Personal Interview | Aspirin (51%) | 0.95 | 0.66–1.35 |
Leitzmann et al. [52] | 2,479 | 47,882b | Cohort | ≥2 tablets per week reported in 4 consecutive questionnaires | Mailed Questionnaire | Aspirin (N.R.) | 1.04 | 0.86–1.26 |
Habel et al. [57] | 2,574 | 90,100b | Cohort | >6 tablets almost ever day | In hospital Questionnaire | Aspirin (2.7%) | 0.76 | 0.60–0.98 |
-
Prevalence of exposure among controls/cohort; §Crude estimate calculated from data provided in the original manuscript; †Genital (includes prostate and testis).