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Table 2 hTERT mRNA expression and hTR in testicular germ cell tumors

From: The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase

Histology No. Telomerase activity Median (25th percentile, 75th percentile) (range) N hTERT * Median (25th percentile, 75th percentile) (range)
ITGCNU 7 0.50 (0.42, 0.53) (0.39–0.55) 43.1 (29.4, 67.8) (13.0 – 74.0)
Seminoma 13 0.45 (0.31, 0.63) (0.19–0.73) 42.3 (30.9, 50.9) (20.0 – 58.9)
EC 9 0.55 (0.47, 0.63) (0.42–0.74) 73.6 (63.4, 88,7) (56.0 – 99.7)
Yolk sac tumor 4 0.39 (0.34, 0.46) (0.3–0.53) 37.7 (24.8, 49.4) (22.4 – 51.4)
Immature teratoma 6 0.52 (0.34–0.70) 52.6 (42.8, 63.4) (42.5–76.0)
Choriocarcinoma 2 0.42 (0.3, 0.55) 37.6 (32.8 and 42.3)
Mature teratoma 8 0.03 (0.01, 0.05) (0.00 – 0.08) 3.7 (3.1, 4.5) (0 – 6.7)
  1. EC = Embryonal carcinoma; ITGCNU = intratubular germ cell neoplasia, unclassified in more than 30 % of the tubuli. *Normalized hTERT mRNA expression