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Table 3 Summary of molecular genetic alterations

From: Predominance of CIN versus MSI in the development of rectal cancer at young age

Tumor no. DI MSI MSH2 MLH1 B-cat. TP53 KRAS mut.
1 2.1 - + + C - -
2 1.1 - + + C - -
3 1.4 - + + C + 12, GGT->GAT
4 4.5 - + + C + 12, GGT->GTT
5 2.0 - + + C + -
6 1.4 - + + C + 12, GGT->TGT
7 1.7 - + + C - -
8 1.0 + - + M - -
9 1.5 - + + M + -
10 1.0 + - + C + 13, GGC->GAC
11 1.0 - + + C - -
12 1.0 + - + N - -
13 1.6 - + + C - -
14 1.0 - + + N + -
15 1.0 - + + C + -
16 1.0 - + + M + -
17 1.0 - + + M - -
18 1.1 - + + C + -
19 1.1 - + + C + -
20 1.3 - + + N - -
21 1.8 - + + C + -
22 1.3 - + + N - -
23 1.2 - + + C - -
24 1.7 - + + N - -
25 1.0 - + + M + -
26 2.0 - + + N + -
27 1.2 - + + C + 12, GGT->GAT
28 1.6 - + + C + -
29 1.2 - + + C + 12, GGT->AGT
30 1.1 - + + C + -
  1. Abbreviations: DI: DNA index C:cytoplasmic, M:membraneous, N:nuclear