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Figure 3 | BMC Cancer

Figure 3

From: SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation

Figure 3

SC-III3 markedly inhibited tumor growth in vivo. Mice were intraperitoneally injected with 2.5, 5 and 10 mg/kg of SC-III3 once a day for 14 days. Control was treated with normal vehicle, and positive control was intraperitoneally injected with 2.5 mg/kg of doxorubicin. (A) Resected tumor images from the experimental. (B) Tumor volume was measured every 3 days. (C) Tumor mass were weighed. (D) Nude mice weight was recorded once a day. Data were presented as Mean ± SEM, n = 10. The difference were significant at *p < 0.05, **p < 0.01 vs. control.

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BMC Cancer

ISSN: 1471-2407

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