Table 2 Base-case cost estimates ($, year 2013 values) and utilities

Costs

Cost of capecitabine per 500 mg

6.6

Fixed

Local charge

Cost of S-1 per 20 mg

9.6

7.9 - 10.1

Local charge

Cost of oxaliplatin per 50 mg

88.9

77.3 - 464.5

Local charge

Cost of follow-up per unit

56.5

42.3 - 70.6

Calculation

Cost of tests per 6-weeks of adjuvant with S-1

197.8

15.9 - 317.5

[31]

Cost of salvage chemotherapy per 3-week cycle

2334.6

1429.3 - 3323.2

Calculation

Cost of palliative end-of-life care

1460.3

1055.3 - 2085.7

Calculation

Cost of supportive care per cycle

115.2

31.7 - 317.5

Calculation

Cost of ADR per 6-week period of adjuvant with S-1

42.3

7.9 - 79.4

[31]

Cost of ADR per 3-week cycle of adjuvant with XELOX strategy

68.9

15.9 - 158.7

[31]

Cost of hospitalization per 3-week cycle of adjuvant with XELOX strategy

373

238.1 - 793.7

[31]

Utilities

Utility of disease-free survival

0.88

0.8 - 0.97

Measured

Utility of recurrent disease

0.42

0.28 - 0.63

Measured