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Table 2 Overall trends in stability over time and space for confirmed somatic mutations in LGSC*

From: Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas

  Time Time and Space
  LGSC-3 LGSC-11 LGSC-9 LGSC-10 LGSC-12
BRAF G469V     Unstable  
BRAF V600E      Stable
KRAS G12R   Stable    
KRAS G12V Stable    Unstable  
NRAS Q61R    Stable   
SMAD47 R361G      Stable
  1. *Only those mutations observed by two independent technologies (true positives) included.
  2. Note: not all cases included in table as no confirmed somatic mutations in LGSC-2, -4, -5 or -13; mutations in LGSC-6 and -8 only observed by either Ion Torrent or MiSeq.