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Table 2 Overall trends in stability over time and space for confirmed somatic mutations in LGSC*

From: Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas

 

Time

Time and Space

 

LGSC-3

LGSC-11

LGSC-9

LGSC-10

LGSC-12

BRAF G469V

   

Unstable

 

BRAF V600E

    

Stable

KRAS G12R

 

Stable

   

KRAS G12V

Stable

  

Unstable

 

NRAS Q61R

  

Stable

  

SMAD47 R361G

    

Stable

  1. *Only those mutations observed by two independent technologies (true positives) included.
  2. Note: not all cases included in table as no confirmed somatic mutations in LGSC-2, -4, -5 or -13; mutations in LGSC-6 and -8 only observed by either Ion Torrent or MiSeq.
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BMC Cancer

ISSN: 1471-2407

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