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Table 2 Relationship between SIRT1 expression and the clinicopathological features of 99 patients with primary hepatocellular carcinoma

From: Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma

Factor Category Total No. of patients SIRT1 negative (n = 23) SIRT1 positive (n = 76) P
Age (years) >50 44 8 (34.8) 36 (47.4) 0.287
  ≤50 55 15 (65.2) 40 (52.6)  
Gender Male 89 22 (95.7) 67 (88.2) 0.296
  Female 10 1 (4.3) 9 (11.8)  
Size of tumor (cm)* >5 44 6 (26.1) 38 (50.0) 0.043
  ≤5 55 17 (73.9) 38 (50.0)  
Tumor number* Single 68 20 (87.0) 48 (63.2) 0.031
  Multiple 31 3 (13.0) 28 (36.8)  
TBIL (μmol/L) >20 23 4 (17.4) 19 (25.0) 0.449
  ≤20 76 19 (82.6) 57 (75.0)  
HBsAg Positive 96 22 (95.7) 74 (97.4) 0.674
  Negative 3 1 (4.3) 2 (2.6)  
AFP (ng/ml) >400 40 7 (30.4) 33 (44.6) 0.228
  ≤400 57 16 (69.6) 41 (55.4)  
Liver cirrhosis Absent 35 9 (39.1) 26 (34.2) 0.665
  Present 64 14 (60.9) 50 (65.8)  
TNM* I 47 17 (73.9) 30 (39.5) 0.038
  II 18 2 (8.7) 16 (21.1)  
  III 16 2 (8.7) 14 (18.4)  
  IV 18 2 (8.7) 16 (21.1)