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Table 1 Genotypes of seven SNPs in CYP3A5 , ABCB1 and ABCG2

From: Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype

Gene SNP Allele Amino acid Genotype
CYP3A5 rs776746 6986A > G Splice Site AG
ABCB1 rs1128503 1236C > T G412G CT
ABCB1 rs2032582 2677G > T/A A893S/T GT
ABCB1 rs1045642 3435C > T I1145I CT
ABCG2 rs2231137 34G > A V12M GG
ABCG2 rs72552713 376G > A Q126X GG
ABCG2 rs2231142 421C > A Q141K AA