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Table 2 Immunohistochemical results of MMPs and TIMPs in each subtype

From: Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer

Characteristics Tumor subtype Pvalue*
Luminal A (n = 123) Basal-like (n = 31) HER2 (n = 17)
Posistive No/Cases (%) Positive No/Cases (%) Positive No/Cases (%)
MMP 1     
 Tumoral 13/123 (10.6) 3/31 (9.7) 2/17 (11.8) 1.000
 Stromal 96/123 (78.0) 22/31 (71.0) 13/17 (76.5) 0.470
MMP 2     
 Tumoral 47/123 (38.2) 11/31 (35.5) 7/17 (41.2) 0.935
 Stromal 4/123 (3.3) 2/31 (6.5) 0/17 (0) 0.641
MMP 7     
 Tumoral 100/123 (81.3) 31/31 (100) 12/17 (70.6) 0.005
 Stromal 35/123 (28.5) 11/31 (35.5) 5/17 (29.4) 0.767
MMP 9     
 Tumoral 28/123 (22.7) 11/31 (35.5) 12/17 (70.6) 0.000
 Stromal 6/123 (4.9) 0/31 (0) 0/17 (0) 0.507
MMP 11     
 Tumoral 115/123 (93.5) 30/31 (96.8) 17/17 (100) 1.000
 Stromal 101/123 (82.1) 29/31 (93.5) 13/17 (76.5) 0.253
MMP 13     
 Tumoral 45/123 (36.6) 17/31 (54.8) 12/17 (70.6) 0.016
 Stromal 9/123 (7.32) 5/31 (16.1) 5/17 (29.4) 0.016
MMP 14     
 Tumoral 67/123 (54.5) 21/31 (67.7) 12/17 (70.6) 0.331
 Stromal 42/123 (34.1) 5/31 (16.1) 5/17 (29.4) 0.118
TIMP 1     
 Tumoral 64/122 (52.5) 12/31 (38.7) 10/17 (58.8) 0.274
 Stromal 22/122 (18.0) 4/31 (12.9) 2/17 (11.8) 0.748
TIMP 2     
 Tumoral 62/123 (50.4) 16/31 (51.6) 11/17 (64.7) 0.657
 Stromal 16/123 (13.0) 6/31 (19.4) 4/17 (23.5) 0.368
TIMP 3     
 Tumoral 100/123 (81.3) 27/31 (87.1) 16/17 (94.1) 0.605
 Stromal 45/123 (36.6) 18/31 (58.1) 8/17 (47.1) 0.107
  1. * P value obtained using the exact chi-square test.