Table 5 Risk of SPC by first and second cancer site among female patients, France 1989–2004 (N = 129,160)
From: The effect of patient characteristics on second primary cancer risk in France
First cancer site | Second cancer site | O | E | PYR | SIRa | EARa,b | (95% CI) |
|---|---|---|---|---|---|---|---|
Head and neck | Head and neckc | 57 | 0.61 | 7,781 | 93.83 | 72.5 | (54.7-94.1) |
Lung, bronchus and trachea | 51 | 2.71 | 18.81 | 62.1 | (45.3-82.7) | ||
Oesophagus | 20 | 0.41 | 49.33 | 25.2 | (15.2-39.2) | ||
Liver, primary | 5 | 0.69 | 7.25 | 5.5 | (1.2-14.1) | ||
Oesophagus | Head and neck | 10 | 0.14 | 1,244 | 71.04 | 79.3 | (37.4-146.7) |
Colorectum | Breast | 297 | 246.36 | 87,123 | 1.21 | 5.8 | (2.0-9.9) |
Colorectumc | 98 | 67.48 | 1.45 | 3.5 | (1.4-6.0) | ||
Corpus uteri | 66 | 41.93 | 1.57 | 2.8 | (1.0-4.8) | ||
Liver, primary | Lung, bronchus and trachea | 5 | 0.61 | 1,709 | 8.13 | 25.7 | (5.8-64.7) |
Non-Hodgkin’s lymphoma | 3 | 0.53 | 5.62 | 14.4 | (0.4-48.2) | ||
Soft tissue | 2 | 0.06 | 32.96 | 11.3 | (1.0-41.9) | ||
Larynx | Lung, bronchus and trachea | 19 | 0.74 | 1,995 | 25.76 | 91.5 | (53.6-145.0) |
Head and neck | 10 | 0.22 | 45.47 | 49.0 | (22.9-91.1) | ||
Oesophagus | 3 | 0.11 | 26.70 | 14.5 | (2.5-43.4) | ||
Bladder | 3 | 0.28 | 10.73 | 13.6 | (1.6-42.5) | ||
Lung, bronchus and trachea | Head and neck | 10 | 0.99 | 9,446 | 10.09 | 9.5 | (4.0-18.4) |
Bladder | 6 | 1.18 | 5.11 | 5.1 | (1.1-12.6) | ||
Oesophagus | 3 | 0.47 | 6.41 | 2.7 | (0.1-8.8) | ||
Soft tissue | Ovary and uterine adnexa | 4 | 0.86 | 3,951 | 4.68 | 8.0 | (0.6-23.8) |
Melanoma of skin | Breast | 98 | 75.05 | 32,127 | 1.31 | 7.1 | (1.4-13.8) |
Kidney | 15 | 5.32 | 2.82 | 3.0 | (1.0-6.0) | ||
Breast | Corpus uteri | 358 | 147.83 | 351,434 | 2.42 | 6.0 | (5.0-7.1) |
Cervix uteri | Lung, bronchus and trachea | 34 | 7.66 | 28,122 | 4.44 | 9.4 | (5.6-14.2) |
Colorectum | 40 | 22.60 | 1.77 | 6.2 | (2.1-11.3) | ||
Vagina and vulva | 10 | 1.28 | 7.82 | 3.1 | (1.2-6.1) | ||
Leukaemia | 12 | 4.17 | 2.88 | 2.8 | (0.7-6.0) | ||
Bladder | 10 | 2.45 | 4.08 | 2.7 | (0.8-5.7) | ||
Corpus uteri | Breast | 174 | 120.03 | 41,147 | 1.45 | 13.1 | (7.1-19.9) |
Colorectum | 106 | 60.33 | 1.76 | 11.1 | (6.4-16.5) | ||
Lung, bronchus and trachea | 34 | 17.06 | 1.99 | 4.1 | (1.6-7.4) | ||
Vagina and vulva | Cervix uteri | 6 | 0.68 | 4,219 | 8.87 | 12.6 | (3.6-29.4) |
Bladder | 4 | 0.88 | 4.53 | 7.4 | (0.5-22.2) | ||
Head and neck | 3 | 0.47 | 6.37 | 6.0 | (0.3-19.7) | ||
Kidney | Breast | 62 | 46.58 | 17,327 | 1.33 | 8.9 | (0.6-19.0) |
Lung, bronchus and trachea | 16 | 6.61 | 2.42 | 5.4 | (1.5-11.2) | ||
Leukaemia | 11 | 4.07 | 2.70 | 4.0 | (0.8-9.0) | ||
Thyroid gland | 8 | 2.70 | 2.96 | 3.1 | (0.4-7.5) | ||
Thyroid gland | Leukaemia | 13 | 3.95 | 31,397 | 3.29 | 2.9 | (0.9-5.8) |
Hodgkin’s disease | Leukaemia | 5 | 0.50 | 6,930 | 10.05 | 6.5 | (1.6-16.1) |
Non-Hodgkin’s lymphoma | 5 | 0.73 | 6.89 | 6.2 | (1.3-15.8) | ||
Lung, bronchus and trachea | 4 | 0.97 | 4.14 | 4.4 | (0.2-13.4) | ||
Non-Hodgkin’s lymphoma | Stomach | 12 | 5.02 | 22,997 | 2.39 | 3.0 | (0.5-6.9) |
Kidney | 12 | 4.99 | 2.41 | 3.0 | (0.5-6.9) | ||
Chronic lymphatic leukaemia | Breast | 41 | 26.30 | 9,091 | 1.56 | 16.2 | (3.4-32.3) |
Acute myeloid leukaemia | Ovary and uterine adnexa | 3 | 0.48 | 2,491 | 6.26 | 10.1 | (0.5-33.3) |