Table 1 Patient characteristics of both treatment groups
Radiosurgery alone N patients (%) | Radiosurgery + WBRT N patients (%) | P-value | |
|---|---|---|---|
Radiosurgery dose | |||
<20 Gy (n = 63) | 38 (39) | 25 (50) | |
≥20 Gy (n = 85) | 60 (61) | 25 (50) | 0.46 |
Age | |||
≤59 years (n = 76) | 49 (50) | 27 (54) | |
≥60 years (n = 72) | 49 (50) | 23 (46) | 0.86 |
Gender | |||
Female (n = 68) | 47 (48) | 21 (42) | |
Male (n = 80) | 51 (52) | 29 (58) | 0.73 |
ECOG Performance Score | |||
0-1 (n = 93) | 64 (65) | 29 (58) | |
2 (n = 55) | 34 (35) | 21 (42) | 0.68 |
Histology | |||
Adenocarcinoma (n = 92) | 62 (63) | 30 (60) | |
Others (n = 56) | 36 (37) | 20 (40) | 0.89 |
Number of cerebral metastases | |||
1 (n = 90) | 61 (62) | 29 (58) | |
2-3 (n = 58) | 37 (38) | 21 (42) | 0.84 |
Maximum diameter of all cerebral metastases | |||
≤18 mm (n = 75) | 50 (51) | 25 (50) | |
≥19 mm (n = 73) | 48 (49) | 25 (50) | 0.97 |
Main site of cerebral metastases | |||
Supratentorial (n = 127) | 84 (86) | 43 (86) | |
Infratentorial (n = 21) | 14 (14) | 7 (14) | 0.99 |
Extra-cerebral metastases | |||
No (n = 95) | 64 (65) | 31 (62) | |
Yes (n = 53) | 34 (35) | 19 (38) | 0.89 |
Interval from lung cancer diagnosis to irradiation | |||
≤11 months (n = 77) | 51 (52) | 26 (52) | |
≥12 months (n = 71) | 47 (48) | 24 (48) | 0.99 |