Figure 7
Representative FISH images of the JIMT-1 and KPL4 breast cancer cell lines using HER2 /CEP17, STARD3 /CEP17 and TOP2A /CEP17 dual-color probes. Metaphase spreads are shown and boxes indicate representative interphase nuclei for each case. FISH images for the JIMT-1 and KPL4 cells demonstrate HER2 and STARD3 gene amplification, while TOP2A gene amplification was not observed in these cells. Gene signals are red-labeled, CEP17 signals are green-labeled.