Gene expression analysis of the
models after treatment with ET-743. A. Venn Diagramm showed the differentially expressed probes distribution in the two in vivo models. B. Hierarchical clustering applied to the expression matrix of genes modulated in a concordant manner by the treatment in both CHC001PDX/EGI-1 models, using Euclidean distance as similarity metrics and average linkage as linkage method. Genes were median center and divided by standard deviation. NT: not treated mice; TREATED: treated with ET-743.