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Table 1 Baseline patient and disease characteristics in carfilzomib-treated patients reporting a cardiac or vascular-related adverse event

From: Case series discussion of cardiac and vascular events following carfilzomib treatment: possible mechanism, screening, and monitoring

 

Patients N = 12

Age, median years (range)

59 (49–77)

Male sex, %

50

Durie-Salmon stage at diagnosis

 

IA

3

IIA

1

IIIA

7

IIIB

1

ISS stage at diagnosis

 

I

0

II

3

III

3

Unknown

6

Lines of previous anti-MM therapy, median

5

Prior bortezomib, n (%)

11 (92)

Prior autologous stem cell transplant, n (%)

9 (75)

Prior anthracycline, n (%)

3 (25)

  1. ISS, International Staging System; MM, multiple myeloma.