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Table 1 Necrotic fraction in C3H tumours in control and VDA treated mice

From: Treatment with a vascular disrupting agent does not increase recruitment of indium labelled human endothelial outgrowth cells in an experimental tumour model

Treatment

Necrotic fraction

Control

18.8 ± 1.4*

CA4P (25 mg/kg)

25.4 ± 2.6*

Control

9.3 ± 1.9#

CA4P (250 mg/kg)

37.0 ± 4.3#

Control

7.4 ± 3.4§

DMXAA (20 mg/kg)

77.3 ± 4.5§

  1. CA4P: Combrestatin A-4 disodium phosphate; DMXAA: 5,6-dimethylxanthenone-4-acetic acid; *Anja B. Bohn, Lotte B. Bertelsen and Thomas Wittenborn unpublished data; #Murata et al. [22], Radiother. Oncol. 60: 155–161; §Murata et al. [36], Int. J. Hyperthermial. 17: 508–519. Data is presented as mean ± SE.