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Figure 2 | BMC Cancer

Figure 2

From: Cholesterol-conjugated let-7amimics: antitumor efficacy on hepatocellular carcinoma in vitro and in a preclinical orthotopic xenograft model of systemic therapy

Figure 2

Live-cell images. Live-cell images were taken from 24 h to 39 h post-transfection. The parental cells with no treatment were observed as blank controls. Laser confocal images of GFP-labelled live cells (green) were recorded in the 3 groups. Cy5-labelled Chol-let-7a or Chol-miRCtrl appears as distinct red bodies. GFP-labelled living HepG2 or SMMC7721 cells appear green. Dead cells lose their green fluorescence. The images show more dead or apoptotic cells in Chol-let-7a-treated cells (yellow arrows). A: HepG2 cells. B: SMMC7721 cells. Magnification: 160×.

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