Table 1 Inclusion criteria for TARGIT A and RIOP trials
TARGIT A | RIOP | |
|---|---|---|
Age (years) | ≥45 | ≥55 |
Menopausal status | Not required | Required |
Unifocal tumor | Required | Required |
Histology | Invasive ductal carcinoma | Invasive ductal carcinoma |
Tumor size | Suitable for wide local excision (<3.5 cm preferable) | ≤2 cm |
SBR grade 1 and 2, hormone receptor-positive, no vascular invasion, HER2 | Not required | All of these criteria were required |
No known BRCA mutation | Not required | Required |