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Table 1 Clinical and histopathological characteristics of the screening cohort and the validation cohort

From: High miR-449b expression in prostate cancer is associated with biochemical recurrence after radical prostatectomy

Clinical variable

Screening cohort (FF)

Validation cohort (FFPE)

Total number of cancer samples

36

163

Age median(range) Years

63 (46–71)

62(48–72)

Gleason grade

  

  Low (5–6)

17 (47%)

60 (37%)

  Intermediate (7)

15 (42%)

85 (52%)

  High (8–10)

4 (11%)

18 (11%)

Pathological stage

  

  T2a-c

19 (53%)

96 (59%)

  T3a-b

17 (47%)

67 (41%)

Time to recurrence (range) Months

15.6 (1–74)

24 (3–122)

Follow up non-recurrent cases Months

66 (31–80)

65 (48–114)

Recurrence

  

  Yes

22 (61%)

96 (59%)

  No

14 (39%)

67 (41%)

Margin status

  

  Positive

16 (44%)

45 (28%)

  Negative

20 (56%)

118 (72%)

  Pre-operative PSA (range)

16.0 (5.3-42.5)

13.2 (2.1-64.5)

  1. FF: fresh frozen tumors. FFPE: formalin fixed paraffin embedded tumors.