Table 1 Clinical characteristics of patient by anemia status
From: Impact of preoperative anemia on relapse and survival in breast cancer patients
|  | N = 2123 (%) | Hb < 12 g/dL | Hb ≥ 12 g/dL | χ 2 | P |
|---|---|---|---|---|---|
|  |  | n = 535 (25.2%) | n = 1588 (74.8%) |  |  |
Age | Â | Â | Â | Â | Â |
  ≤50 | 1384 (65.2) | 359 (67.1) | 1025 (64.5) | 1.152 | 0.283 |
  >50 | 739 (34.8) | 176 (32.9) | 563 (35.5) |  |  |
Tumor type | Â | Â | Â | Â | Â |
  Invasive ductal carcinoma | 1944 (91.6) | 503 (94.0) | 1441 (90.7) | 5.561 | 0.018 |
  Other | 179 (8.4) | 32 (6.0) | 147 (9.3) |  |  |
Tumor stage | Â | Â | Â | Â | Â |
  T1 | 703 (33.1) | 146 (27.3) | 557 (35.1) | 32.458 | <0.001 |
  T2 | 1146 (54.0) | 284 (53.1) | 862 (54.3) |  |  |
  T3 and T4 | 274 (12.9) | 105 (19.6) | 169 (10.6) |  |  |
N stage | Â | Â | Â | Â | Â |
  N0 | 1185 (55.8) | 250 (46.7) | 935 (58.8) | 38.534 | <0.001 |
  N1 | 603 (28.4) | 159 (29.7) | 444 (28.0) |  |  |
  N2 | 211 (9.9) | 78 (14.6) | 133 (8.4) |  |  |
  N3 | 124 (5.8) | 48 (9.0) | 76 (4.8) |  |  |
Histologic grading | Â | Â | Â | Â | Â |
  G1G2 or Gx | 1680 (79.1) | 425 (79.4) | 1255 (79.0) | 0.041 | 0.840 |
  G3 | 443 (20.9) | 110 (20.6) | 333 (21.0) |  |  |
ER | Â | Â | Â | Â | Â |
  Negative | 846 (39.8) | 226 (42.3) | 620 (39.1) | 6.385 | 0.041 |
  Positive | 683 (32.2) | 182 (34.0) | 501 (31.5) |  |  |
  Strongly positive | 594 (28.0) | 127 (23.7) | 467 (29.4) |  |  |
PR | Â | Â | Â | Â | Â |
  Negative | 654 (30.8) | 168 (31.4) | 486 (30.6) | 8.078 | 0.018 |
  Positive | 906 (42.7) | 249 (46.5) | 657 (41.4) |  |  |
  Strongly positive | 563 (26.5) | 118 (22.1) | 445 (28.0) |  |  |
HER-2 | Â | Â | Â | Â | Â |
  Negative | 1067 (50.3) | 249 (46.5) | 818 (51.5) | 10.315 | 0.006 |
  Positive | 633 (29.8) | 154 (28.8) | 479 (30.2) |  |  |
  Strongly positive | 423 (19.9) | 132 (24.7) | 291 (18.3) |  |  |
BMI | Â | Â | Â | Â | Â |
  Low (<18.5) | 151 (7.1) | 47 (8.8) | 104 (6.6) | 25.980 | <0.001 |
  Normal (18.5–22.9) | 929 (43.8) | 276 (51.6) | 653 (41.1) |  |  |
  High (>22.9) | 1043 (49.1) | 212 (39.6) | 831 (52.3) |  |  |
Menopause | Â | Â | Â | Â | Â |
  No | 1318 (62.1) | 352 (65.8) | 966 (60.8) | 4.188 | 0.041 |
  Yes | 805 (37.9) | 183 (34.2) | 622 (39.2) |  |  |
Type of surgery | Â | Â | Â | Â | Â |
  Modified radical mastectomy | 2092 (98.5) | 531 (99.3) | 1561 (98.3) | 2.524 | 0.112 |
  Breast-conserving surgery | 31 (1.5) | 4 (0.7) | 27 (1.7) |  |  |
Chemotherapy | Â | Â | Â | Â | Â |
  No | 381 (17.9) | 89 (16.6) | 292 (18.4) | 0.835 | 0.361 |
  Yes | 1742 (82.1) | 446 (83.4) | 1296 (81.6) |  |  |
Radiotherapy | Â | Â | Â | Â | Â |
  No | 1842 (86.8) | 452 (84.5) | 1390 (87.5) | 3.232 | 0.072 |
  Yes | 281 (13.2) | 83 (15.5) | 198 (12.5) |  |  |
Hormonal therapy | Â | Â | Â | Â | Â |
  No | 1366 (64.3) | 347 (64.9) | 1019 (64.2) | 0.083 | 0.773 |
  Yes | 757 (35.7) | 188 (35.1) | 569 (35.8) |  |  |
Targeted therapy | Â | Â | Â | Â | Â |
  No | 2109 (99.3) | 530 (99.1) | 1579 (99.4) | - | 0.361a |
  Yes | 14 (0.7) | 5 (0.9) | 9 (0.6) |  |  |