Figure 6From: Dexrazoxane may prevent doxorubicin-induced DNA damage via depleting both Topoisomerase II isoforms TOP2A protein levels in response to DRZ. 24 h incubation with 100 μM DRZ in HT1080 (A), NYH (B), HEK293 (C), and in differentiated H9C2 cells. The lower panel of (D) additionally shows the effect of incubation time in H9C2 cells.Back to article page