Figure 1

Association of FOXP1 expression levels with prognostic markers and patient outcome in 476 neuroblastomas as determined by microarray analysis. Association of (a) tumor stage, (b) age at diagnosis, (c) MYCN amplification status and (d) gene expression-based classification (PAM classifier) [26] with FOXP1 transcript levels. Boxes, median expression values (horizontal line) and 25th and 75th percentiles; whiskers, distances from the end of the box to the largest and smallest observed values that are less than 1.5 box lengths from either end of the box; open circles, outlying values. Survival curves of neuroblastoma patients for (e) EFS and (f) OS according to FOXP1 expression as determined by microarray analysis. N, patient numbers; amp, amplified; fav, favorable; unfav, unfavorable.