Figure 2

Representative DNA sequencing chromatographs and schematic drawings showing EML4-ALK fusion junctions. Five EML4-ALK fusion transcript variants were detected by one-step real time RT-PCR. The DNA sequences and their sequencing traces are shown for each detected fusion transcripts: V1 (A), V2 (B), V3a (C), V4a (D), and V5a (E). The Case ID is also indicated for each sample. Schematic drawings showing the organization of fusion junctions are shown below the corresponding DNA sequences.