WBC with methylated
show similar epigenetic changes in both breast cancer cases and carriers (A) a heat map comparing the methylation status of a panel of 10 cancer-related genes in WBC from controls C, breast cancer BC, and carriers CR as determined using Human Breast Cancer EpiTect Methyl II Signature PCR Array. The red color represents values of +2.5 fold relative to controls (B) Comparison between quantitative analysis of methylation for the candidate genes in the studied cohort; Controls (n = 10), Breast cancer (n = 17) and Carriers (n = 9). Significant correlation; Chi square. Numbers represent p values. Error bars represent the mean ± SD.