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Figure 3 | BMC Cancer

Figure 3

From: Platinum sensitivity and CD133 expression as risk and prognostic predictors of central nervous system metastases in patients with epithelial ovarian cancer

Figure 3

Kaplan–Meier curves of cumulative overall survival after the diagnosis of central nervous system (CNS) metastases in 29 patients with CNS metastases from ovarian cancer. (A) Platinum-resistant vs. platinum-sensitive disease. Result of multivariate Cox regression; HR, 5.13; 95% CI, 1.28-20.57; P = 0.021. (B) Multimodal therapy including stereotactic radiosurgery (SRS) vs. multimodal therapy including whole-brain radiation therapy (WBRT) vs. unimodal therapy with WBRT or neurosurgery vs. steroids. Result of multivariate Cox regression; multimodal therapy including SRS vs. others: HR, 0.12; 95% CI, 0.03-0.55; P = 0.007. (C) CD133 cluster formation vs. CD133 negative or single cell. Result of multivariate Cox regression; HR, 12.08; 95% CI, 1.55-94.16; P = 0.017.

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BMC Cancer

ISSN: 1471-2407

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