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Table 3 Univariate and multivariate Cox proportional hazards regression model for death

From: Emerging markers of cachexia predict survival in cancer patients

 

Univariate analysis

Multivariate analysis

p value

 

HR

95% CI

x 2

p value

HR

95% CI

x 2

 

Leptin

0.92

0.88 – 0.95

5.36

0.0006

0.94

0.92 – 0.96

4.65

0.0001

Ghrelin

1.01

1.00 – 1.01

2.87

0.005

1.02

1.01 – 1.03

5.81

< 0.0001

Obestatin

1.13

1.03 – 1.24

3.71

0.009

1.04

0.99 – 1.10

1.05

0.10

Albumin

1.66

0.81 – 3.40

1.23

0.16

    

CKD

2.19

1.11 – 4.34

2.37

0.02

1.97

1.24 – 3.12

2.14

0.003

Metastasis

1.15

1.25 – 8.02

2.12

0.01

2.67

1.45 – 4.91

3.86

0.001

Age

1.00

0.95 – 1.04

0.16

0.95

1.00

0.95 – 1.01

0.15

0.93

Weight change

0.90

0.82 – 1.00

0.27

0.90

    

Hemoglobin

0.99

0.86 – 1.15

0.12

0.97

    
  1. HR: hazard ratio; CI: confidence interval; CKD: chronic kidney disease.
  2. Weight change was measured from baseline to 18 months follow-up.