Figure 3

Kaplan–Meier all-cause mortality curves. A Kaplan-Meier survival curves of end-point (mortality during a median follow-up period of 18 months) in patients with ghrelin, leptin, albumin and obestatin levels above and below the optimal receiver operating characteristics cut-off level. Patients with ghrelin >663 ng/ml showed a significantly faster progression to endpoint (log-rank (χ²) 5.02; p = 0.02) B Association of ghrelin, leptin or albumin to provide the best predictive model of mortality. Patients with high levels of ghrelin and low leptin levels were characterized by the worst outcome (log-rank (χ²) 8.02; p = 0.004). Patients with low levels of ghrelin and high levels of albumin instead had the best profile, although there were no statistically significant differences if compared with patients with low levels of ghrelin and high levels.