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Table 4 Correlation of clinicopathological charateristics in IDC patients with Ki67 ≤ 5% vs. ≥10%

From: Lobular breast cancers lack the inverse relationship between ER/PR status and cell growth rate characteristic of ductal cancers in two independent patient cohorts: implications for tumor biology and adjuvant therapy

  

All IDC

AUS-IDC

HK-IDC

Characteristics

No. with Ki67 ≤ 5 (%)

No. with Ki67 ≥ 10 (%)

p

No. with Ki67 ≤ 5 (%)

No. with Ki67 ≥ 10 (%)

p

No. with Ki67 ≤ 5 (%)

No. with Ki67 ≥ 10 (%)

p

Tumor size

         
 

Median (range)

1.4 (0.01 – 10.0)

2.0 (0.01 – 14.5)

<0.0005

1.5 (0.2 - 6.5)

2.2 (0.2 - 14.5)

<0.0005

1.3 (0.01 - 10.0)

1.9 (0.01 - 10.0)

<0.0005

LN involvement

         
 

Negative

177 (69.1%)

493 (56.6%)

<0.0005

33 (66%)

66 (46.5%)

0.018

144 (69.9%)

427 (58.6%)

0.003

 

Positive

79 (30.9%)

378 (43.4%)

 

17 (34%)

76 (53.5%)

 

62 (30.1%)

302 (41.4%)

 

ER

         
 

Negative

13 (4.9%)

270 (30.0%)

<0.0005

1 (1.8%)

35 (21.6%)

0.001

12 (5.7%)

235 (31.8%)

<0.0005

 

Positive

252 (95.1%)

630 (70.0%)

 

54 (98.2%)

127 (78.4%)

 

198 (94.3%)

503 (68.2%)

 

PR

         
 

Negative

27 (10.2%)

313 (34.9%)

<0.0005

3 (5.4%)

40 (25.0%)

0.002

24 (11.4%)

273 (37.0%)

<0.0005

 

Positive

239 (89.8%)

585 (65.1%)

 

53 (94.6%)

120 (75.0%)

 

186 (88.6%)

465 (63.0%)

 

HER2

         
 

Negative

243 (92.0%)

650 (73.0%)

<0.0005

54 (98.2%)

125 (78.1%)

0.001

189 (90.4%)

525 (71.8%)

<0.0005

 

Positive

21 (8.0%)

241 (27.0%)

 

1 (1.8%)

35 (21.9%)

 

20 (9.6%)

206 (28.2%)

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