Table 4 Critical comparisons of specific input and output characteristics for three different in vitro migration assays
Scratch/wound healing | Boyden/transwell | Aligned nanofiber | |
|---|---|---|---|
Sample Pool for Analysis | Confluent monolayer | Individual cells | Individual cells/tumor tissue |
Biomimetic | (-) | (-) | (+) |
Proliferation Dependent | (+) | (+) | (-) |
Chemotaxis | (-) | (+) | (+) |
Output | % of scratch remaining | Cell count | Net and total distance (μm) |
Velocity Assessment | % area closed w/r/t time | NA | Velocity (μm/h) |