Skip to main content

Table 2 The expression of p53, ERCC1, beta-tubulin and bcl-2 stratified by HPV and p16 status

From: Different protein expression associated with chemotherapy response in oropharyngeal cancer according to HPV status

  Total n(%) HPV status, n(%) p16 status, n(%)
Positive Negative p Positive Negative p
p53     <0.001    <0.001
 Low 49 (66) 20 (95) 29 (55) 32 (91) 17 (44)
 High 25 (34) 1 (5) 24 (45) 3 (9) 22 (56)
ERCC1     0.329    0.422
 Low 34 (46) 11 (52) 23 (43) 17 (49) 17 (44)
 High 40 (54) 10 (48) 30 (57) 18 (51) 22 (56)
Class III beta tubulin     0.002    0.001
 Low 52 (70) 20 (95) 32 (60) 31 (89) 21 (54)
 High 22 (30) 1 (5) 21 (40) 4 (11) 18 (46)
Bcl-2     0.003    0.006
 Low 57 (77) 11 (52) 46 (87) 22 (63) 35 (90)
 High 17 (23) 10 (48) 7 (13)   13 (37) 4 (10)