| Lauren classification | P# value | HER2 status | P* value | |||
---|---|---|---|---|---|---|---|
Diffuse(%) | Intestinal(%) | Mixed(%) | Negative(%) | Positive(%) | |||
Sex | Â | Â | Â | <0.0 | Â | Â | Â |
Male | 242 (43.7) | 216 (39.0) | 96 (17.3) | 01 | 486 (87.7) | 68 (12.3) | 0.176 |
Female | 185 (64.7) | 68 (23.9) | 31 (10.9) | 258 (90.8) | 26 (9.2) | ||
Age | Â | Â | Â | <0.001 | Â | Â | <0.001 |
≤59 | 269 (62.7) | 104 (24.2) | 56 (13.1) | 398 (92.8) | 31 (7.2) | ||
>59 | 158 (38.6) | 180 (44.0) | 71 (17.4) | 346 (84.6) | 63 (15.4) | ||
Stage | Â | Â | Â | <0.001 | Â | Â | 0.406 |
I | 68 (47.9) | 60 (42.3) | 14 (9.8) | 131(92.3) | 11 (7.7) | ||
II | 96 (41.7) | 102 (44.3) | 32 (13.9) | 203 (88.3) | 27 (11.7) | ||
III | 215 (56.9) | 95 (25.1) | 68 (18.0) | 335 (88.6) | 43 (11.4) | ||
IV | 48 (54.5) | 27 (30.7) | 13 (14.8) | 75 (85.2) | 13 (14.8) | ||
Degree of differentiation | Â | Â | Â | <0.001 | Â | Â | <0.001 |
Well + Moderate | 0 (0) | 262 (76.2) | 82 (23.8) | 270 (78.5) | 74 (21.5) | ||
Poor + signet ring cell | 427 (86.4) | 22 (4.5) | 45 (9.1) | 474 (96.0) | 20 (4.0) | ||
Location | Â | Â | Â | <0.001 | Â | Â | <0.001 |
Proximal | 110 (35.9) | 146 (47.7) | 50 (16.3) | 251 (82.0) | 55 (18.0) | ||
Distal | 276 (59.1) | 128 (27.4) | 63 (13.5) | 436 (93.4) | 31 (6.6) | ||
Total stomach | 41 (63.1) | 10 (15.4) | 14 (21.5) | 57 (87.7) | 8 (12.3) | ||
Adjuvant chemotherapy | Â | Â | Â | Â | Â | Â | Â |
Yes | 302 (51.4) | 192 (32.7) | 94 (15.9) | Â | 531 (90.3) | 57 (9.7) | Â |
No | 77 (47.5) | 65 (40.1) | 20 (12.4) | 0.170 | 138 (85.2) | 24 (14.8) | 0.063 |