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Table 1 Baseline characteristics

From: Lauren classification combined with HER2 status is a better prognostic factor in Chinese gastric cancer patients

 

Lauren classification

P# value

HER2 status

P* value

Diffuse(%)

Intestinal(%)

Mixed(%)

Negative(%)

Positive(%)

Sex

   

<0.0

   

Male

242 (43.7)

216 (39.0)

96 (17.3)

01

486 (87.7)

68 (12.3)

0.176

Female

185 (64.7)

68 (23.9)

31 (10.9)

258 (90.8)

26 (9.2)

Age

   

<0.001

  

<0.001

≤59

269 (62.7)

104 (24.2)

56 (13.1)

398 (92.8)

31 (7.2)

>59

158 (38.6)

180 (44.0)

71 (17.4)

346 (84.6)

63 (15.4)

Stage

   

<0.001

  

0.406

I

68 (47.9)

60 (42.3)

14 (9.8)

131(92.3)

11 (7.7)

II

96 (41.7)

102 (44.3)

32 (13.9)

203 (88.3)

27 (11.7)

III

215 (56.9)

95 (25.1)

68 (18.0)

335 (88.6)

43 (11.4)

IV

48 (54.5)

27 (30.7)

13 (14.8)

75 (85.2)

13 (14.8)

Degree of differentiation

   

<0.001

  

<0.001

Well + Moderate

0 (0)

262 (76.2)

82 (23.8)

270 (78.5)

74 (21.5)

Poor + signet ring cell

427 (86.4)

22 (4.5)

45 (9.1)

474 (96.0)

20 (4.0)

Location

   

<0.001

  

<0.001

Proximal

110 (35.9)

146 (47.7)

50 (16.3)

251 (82.0)

55 (18.0)

Distal

276 (59.1)

128 (27.4)

63 (13.5)

436 (93.4)

31 (6.6)

Total stomach

41 (63.1)

10 (15.4)

14 (21.5)

57 (87.7)

8 (12.3)

Adjuvant chemotherapy

       

Yes

302 (51.4)

192 (32.7)

94 (15.9)

 

531 (90.3)

57 (9.7)

 

No

77 (47.5)

65 (40.1)

20 (12.4)

0.170

138 (85.2)

24 (14.8)

0.063

  1. HER2: human epidermal growth factor receptor 2.
  2. #P values of Lauren classification in different clinical features. *P values of HER 2 status in different clinical features.