Table 1 Multivariate analysis of ROCK1 expression and clinicopathological characteristics in patients with vulvar SCC

Histologic types

SCC1, SCC2, Verrucous Ca (1)

76

1

1

0.6177

SCC3, Basaloid Ca, Sarcomatoid Ca(2)

20

0.78

0.30 - 2.05

FIGO stage

IA, IB, II (1)

54

1

1

0.2083

IIA, IIIB, IIIC, IVA, IVB (2)

40

1.62

0.76 - 3.47

HPV

Absent (0)

50

1

1

0.2238

Present (1)

46

0.63

0.30 - 1.33

Inflammatory infiltrate

Absent (0)

38

1

1

0.4964

Present (1)

58

0.77

0.36 - 1.64

Vascular Invasion

Absent (0)

74

1

1

0.0365*

Present (1)

17

2.22

1.03 - 4.77

Perineural invasion

Absent (0)

76

1

1

0.4178

Present (1)

12

1.43

0.60 - 3.38

ROCK1 CT

Weak expression

22

1

1

0.6653

Moderate expression

55

0.70

0.28 - 1.75

Strong expression

19

0.95

0.34 - 2.67

ROCK1 IF

Weak expression

8

1

1

0.0054*

Moderate expression

53

0.22

0.08 - 0.60

Strong expression

35

0.30

0.11 -0.84