Table 4 Cancer-specific and all-cause survival by category of comorbidity among those with Stage I-III disease

Impact of comorbidity evaluated at C3 Score of:*

Unadjusted

Model 1¹

Model 2²

0

1.00

1.00

1.00

1

1.38 (1.11-1.71)

1.33 (1.04-1.71)

1.24 (0.96-1.6)

2

1.68 (1.2-2.36)

1.56 (1.05-2.31)

1.36 (0.91-2.04)

3

1.86 (1.26-2.74)

1.62 (1.03-2.54)

1.34 (0.84-2.13)

6

1.68 (1.08-2.61)

1.15 (0.71-1.87)

0.85 (0.51-1.4)

All-cause mortality Hazard Ratios (95% CI)

C3 score*

Unadjusted

Model 1¹

Model 2²

0

1.00

1.00

1.00

1

1.30 (1.06-1.6)

1.25 (0.99-1.58)

1.17 (0.92-1.48)

2

1.57 (1.14-2.17)

1.43 (0.99-2.07)

1.27 (0.87-1.85)

3

1.77 (1.23-2.56)

1.54 (1.01-2.35)

1.28 (0.83-1.99)

6

1.97 (1.33-2.9)

1.44 (0.93-2.23)

1.04 (0.66-1.63)