Figure 6
From: Effects of insulin on human pancreatic cancer progression modeled in vitro
Effects of insulin analogues on PANC1 cell viability. (A) Effects of recombinant insulin, insulin Lispro, and insulin Glargine on AKT phosphorylation after 60 minutes (n =16). Two-tailed paired sample t-test revealed insulin Glargine promoted greater stimulation of AKT phosphorylation than recombinant insulin at the 200 nM insulin concentration denoted by # ( p < 0.05). (B) Cell viability assessed by XTT assay on PANC1 cells treated with insulin analogues for 24 hours (n =8). Two-tailed t-test were performed, and * denotes statistical significance when compared to non-treated condition.