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Table 3 Cervical cell folate concentrations [ng/mg protein] according to case or control status, and cytology

From: Tumour suppressor gene methylation and cervical cell folate concentration are determinants of high-risk human papillomavirus persistence: a nested case control study

  

Normal cytology

Borderline abnormality

Mild abnormality

Mild + Borderline

All

Cases

n

61

25

25

50

111

median

3.23

2.28

3.88**

3.11

3.21

interquartile range

1.88-7.08

0.73-6.11

2.16-6.94

1.00-6.77

1.80-7.03

Controls

n

61

20

25

45

106

median

3.60

2.97

2.33

2.50

3.03

interquartile range

2.30-6.00

2.12-4.89

1.02-3.55

1.47-4.10

1.83-5.42

All

n

122

45

50

95

217

median

3.41

2.68

2.72

2.68*

3.07

interquartile range

1.94-6.72

0.92-6.11

1.36-5.82

1.22-6.11

1.81-6.21

  1. A total of 556 cervical cell samples were used for folate measurements, 2–3 samples were pooled for these measurements, n values refer to the number of actual measurements made.
  2. *Significantly lower than in women with normal cytology [P = 0.002].
  3. **Significantly higher than in controls [P = 0.004].