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Table 3 Cervical cell folate concentrations [ng/mg protein] according to case or control status, and cytology

From: Tumour suppressor gene methylation and cervical cell folate concentration are determinants of high-risk human papillomavirus persistence: a nested case control study

   Normal cytology Borderline abnormality Mild abnormality Mild + Borderline All
Cases n 61 25 25 50 111
median 3.23 2.28 3.88** 3.11 3.21
interquartile range 1.88-7.08 0.73-6.11 2.16-6.94 1.00-6.77 1.80-7.03
Controls n 61 20 25 45 106
median 3.60 2.97 2.33 2.50 3.03
interquartile range 2.30-6.00 2.12-4.89 1.02-3.55 1.47-4.10 1.83-5.42
All n 122 45 50 95 217
median 3.41 2.68 2.72 2.68* 3.07
interquartile range 1.94-6.72 0.92-6.11 1.36-5.82 1.22-6.11 1.81-6.21
  1. A total of 556 cervical cell samples were used for folate measurements, 2–3 samples were pooled for these measurements, n values refer to the number of actual measurements made.
  2. *Significantly lower than in women with normal cytology [P = 0.002].
  3. **Significantly higher than in controls [P = 0.004].